Most medications used to treat hypothyroidism are tablets.13 In addition to levothyroxine, they contain a variety of excipients (inactive ingredients) such as wheat starch (gluten), lactose, sugars, dyes, and talc. There have been instances where these ingredients cause irritation or make it harder for your body to absorb your thyroid medicine. Tirosint-SOL is a unique levothyroxine formulation that contains only 3 ingredients—levothyroxine, glycerol, and water. Unlike other levothyroxine medications used to treat hypothyroidism that come in tablet form, Tirosint-SOL is a pleasant-tasting liquid. Tirosint-SOL is taken orally and contains no alcohol. It is FDA-approved for patients of any age.3

See the list below of common excipients not found in Tirosint-SOL.

The widest range of doses of any levothyroxine therapy

For flexible dosing options, IBSA offers 15 different dosage strengths of Tirosint-SOL, including NEW 37.5, 44 and 62.5 mcg doses. Now with the widest range of doses of any levothyroxine therapy, Tirosint-SOL enables your doctor to prescribe the exact dosage that is right for you.

Tirosint-SOL is available in convenient 30-count cartons. Every Tirosint-SOL carton is color-coded for dosage strength, to make it easier for you and your pharmacy to ensure that you get the same dosage of Tirosint-SOL that your doctor has prescribed.7

Excipients found in other levothyroxine preparations

  • Modified wheat starch (gluten)
  • Lactose monohydrate
  • Dyes
  • Confectioners’ sugar (contains cornstarch)
  • Microcrystalline cellulose
  • Butylated hydroxyanisole (BHA)
  • Talc
  • Croscarmellose sodium
  • Calcium phosphate dibasic
  • Colloidal silicon dioxide
  • Mannitol
  • Crospovidone
  • Magnesium stearate
  • Acacia
  • Sucrose
  • Povidone
  • Sodium lauryl sulfate


Everyone is paying closer attention to the ingredients found in the foods we consume these days, so it only makes sense to do the same with medication. For people with serious food allergies or restrictions, exposure to even small quantities of certain ingredients may cause a serious reaction.4 In a recent survey of nearly 1,000 patients taking levothyroxine to treat their hypothyroidism, 15% of respondents reported allergies to the excipients commonly found in levothyroxine tablets.5

For people with food or ingredient sensitivities, Tirosint-SOL offers effective relief of hypothyroidism without sugars, dyes, alcohol, wheat starch (gluten), lactose, or any other excipients (inactive ingredients) used to make traditional levothyroxine tablets. It is produced in a dedicated facility, where no other products are made, reducing the risk of cross-contamination and providing you with additional peace of mind.6


The story doesn’t end there. People who have gastrointestinal (GI) diseases or who are taking certain medications can have problems with consistently absorbing levothyroxine therapy. Tirosint-SOL has been clinically shown to be less affected by some stomach medications like proton pump inhibitors than other formulations of levothyroxine.10 For some patients this means that Tirosint-SOL may offer more consistent control of hypothyroid symptoms than similar doses of levothyroxine. Simply stated, Tirosint-SOL does not contain excipients that can interfere with how well your body absorbs your thyroid medication, which ultimately can affect how well you feel.4

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